No single hypothesis in isolation is likely to offer much greater insight into the full nature of cancer. Advances require pillars on which to build, but if these are inadequate, progress is slow and clinical interventions are too often based on trial and error than a sound scientific basis. We have established a considerable knowledge of much that goes on in the field of cancer, which is why this new journal is being introduced. The “we” are many colleagues who have served previously on our editorial boards for related journals and other new members invited to join us. Our editorial office has been operating for over 18 years with a very experienced staff to handle new papers quickly and efficiently, thereby giving the opportunity to publish papers online within a few weeks or months, whereas other journals often take up to a year to handle theoretical manuscripts. This venture operates through the editorial staff of BioMedES (www.biomedes.co.uk) and Oncology News (www.oncology news.biz) - a free online journal published on a not-for-profit basis.
Hypotheses are questions; greater understanding in any field of life depends on not only asking lots of questions, but in selecting - based on observation, experience and experiment – the most apposite, as Linus Pauling emphasised many years ago. Sometimes ideas come from correlations that had been expected, sometimes from unexpected ones, and occasionally from obscure origins when hunches and lateral thinking seem to be involved. Cancer Hypotheses therefore sees no hypothesis as sacrosanct (“written in stone”); some may have elements of truth in them, but even these need to be constantly refined and updated. Others may seem quite bizarre, as when that “awkward little fact” that crops up from an experiment can lead to the complete revision of a hypothesis. It can also be a case where the crazy idea of today becomes the received wisdom of tomorrow.
We need a forum that brings together developments of some extant hypotheses along with many new ideas about all aspects of cancer, which is the underlying reason for having such a journal. It must allow free expression, from challenges to present thinking right through to the more bizarre ideas just mentioned. We will therefore embrace a wide spectrum of papers coming from individuals and research groups. If papers do spark off interest from one to another, perhaps this alone will lead to new avenues of exploration which could in due course lead to useful knowledge in the prevention and treatment of this complex disease.
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